Sladek, Franc: search on Z-Library

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1

Nuclear Receptors as Drug Targets: New Developments in Coregulators, Orphan Receptors and Major Therapeutic Areas

Sladek, Frances M

Journal:

Expert Opinion on Therapeutic Targets

Year:

2003

Language:

english

File:

PDF, 87 KB

english, 2003

2

Conservation of DNA and Ligand Binding Properties of Retinoid X Receptor from the Placozoan Trichoplax adhaerens to human

Reitzel, Adam M., Macrander, Jason, Mane-Padros, Daniel, Fang, Bin, Sladek, Frances M., Tarrant, Ann M.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2018

Language:

english

File:

PDF, 927 KB

english, 2018

3

Functional characterization of the HNF4α isoform (HNF4α8) expressed in pancreatic β-cells

Arisa Ihara, Kazuya Yamagata, Takao Nammo, Atsuko Miura, Ming Yuan, Toshiya Tanaka, Frances M. Sladek, Yuji Matsuzawa, Jun-ichiro Miyagawa, Iichiro Shimomura

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 626 KB

english, 2005

4

MORPHEUS, a Webtool for Transcription Factor Binding Analysis Using Position Weight Matrices with Dependency

Minguet, Eugenio Gómez, Segard, Stéphane, Charavay, Céline, Parcy, François, Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

5

Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver

Deol, Poonamjot, Yang, Jun, Morisseau, Christophe, Hammock, Bruce D., Sladek, Frances M.

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 996 KB

english, 2019

6

Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver

Deol, Poonamjot, Evans, Jane R., Dhahbi, Joseph, Chellappa, Karthikeyani, Han, Diana S., Spindler, Stephen, Sladek, Frances M., Peterson, Jonathan

Journal:

Year:

2015

Language:

english

File:

PDF, 3.65 MB

english, 2015

7

Serine/Threonine Phosphorylation of Orphan Receptor Hepatocyte Nuclear Factor 4

Guoqiang Jiang, Luviminda Nepomuceno, Qing Yang, Frances M. Sladek

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 2.42 MB

english, 1997

8

Differential effects of HNF4α isoforms on tumor growth and TCF4/AP-1 interactions in human colorectal cancer cells

Vuong, Linh M., Chellappa, Karthikeyani, Dhahbi, Joseph M., Deans, Jonathan R., Fang, Bin, Bolotin, Eugene, Titova, Nina V., Hoverter, Nate P., Spindler, Stephen R., Waterman, Marian L., Sladek, Franc

Journal:

Molecular and Cellular Biology

Year:

2015

Language:

english

File:

PDF, 7.80 MB

english, 2015

9

Alterations of Epigenetic Signatures in Hepatocyte Nuclear Factor 4α Deficient Mouse Liver Determined by Improved ChIP-qPCR and (h)MeDIP-qPCR Assays

Zhang, Qinghao, Lei, Xiaohong, Lu, Hong, Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.07 MB

english, 2014

10

NSIT: Novel Sequence Identification Tool

Pupacdi, Benjarath, Javed, Asif, Zaki, Mohammed J., Ruchirawat, Mathuros, Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 683 KB

english, 2014

11

Incision by UvrABC Excinuclease is a Step in the Path to Mutagenesis by Psoralen Crosslinks in Escherichia coli

Frances M. Sladek, Agustin Melian and Paul Howard-Flanders

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 1.14 MB

english, 1989

12

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs

Allevato, Michael, Bolotin, Eugene, Grossman, Mark, Mane-Padros, Daniel, Sladek, Frances M., Martinez, Ernest, Hayes, Finbarr

Journal:

Year:

2017

Language:

english

File:

PDF, 7.58 MB

english, 2017

13

Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4α in rat liver

Bin Wang, Shi-Rong Cai, Cuihua Gao, Frances M. Sladek, Katherine Parker Ponder

Journal:

Year:

2001

Language:

english

File:

PDF, 805 KB

english, 2001

14

The Polymorphic AluYb8 Insertion in the MUTYH Gene is Associated with Reduced Type 1 Protein Expression and Reduced Mitochondrial DNA Content

Guo, Wenwen, Zheng, Bixia, Cai, Zhenming, Xu, Lizhi, Guo, Dong, Cao, Lili, Wang, Yaping, Sladek, Frances M.

Journal:

Year:

2013

Language:

english

File:

PDF, 5.03 MB

english, 2013

15

Polyamines Modulate the Interaction between Nuclear Receptors and Vitamin D Receptor-Interacting Protein 205

Maeda, Yutaka, Rachez, Christophe, Hawel, Leo, Byus, Craig V., Freedman, Leonard P., Sladek, Frances M.

Journal:

Molecular Endocrinology

Year:

2002

Language:

english

File:

PDF, 329 KB

english, 2002

16

The yin and yang of proliferation and differentiation

Sladek, Frances M.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.26 MB

english, 2012

17

A Random Screen Using a Novel Reporter Assay System Reveals a Set of Sequences That Are Preferred as the TATA or TATA-Like Elements in the CYC1 Promoter of Saccharomyces cerevisiae

Watanabe, Kiyoshi, Yabe, Makoto, Kasahara, Koji, Kokubo, Tetsuro, Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 3.89 MB

english, 2015

18

The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells

Wong, Tsz Yan, Lin, Shu-mei, Leung, Lai K., Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.84 MB

english, 2015

19

What are nuclear receptor ligands?

Frances M. Sladek

Journal:

Molecular and Cellular Endocrinology

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

20

Disruption of a Binding Site for Hepatocyte Nuclear Factor 4 Results in Hemophilia B Leyden

Marlene J. Reijnen, Frances M. Sladek, Rogier M. Bertina and Pieter H. Reitsma

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 834 KB

english, 1992

21

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4α (HNF4α) gene

Maeda, Yutaka, Hwang-Verslues, Wendy W., Wei, Gang, Fukazawa, Takuya, Durbin, Mary L., Owen, Laurie B., Liu, Xuan, Sladek, Frances M.

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 687 KB

english, 2006

22

Repression of Hepatocyte Nuclear Factor 4α by Tumor Suppressor p53: Involvement of the Ligand-Binding Domain and Histone Deacetylase Activity

Maeda, Yutaka, Seidel, Shawn D., Wei, Gang, Liu, Xuan, Sladek, Frances M.

Journal:

Molecular Endocrinology

Year:

2002

Language:

english

File:

PDF, 292 KB

english, 2002

23

Hepatocyte Nuclear Factor 4 Alpha Polymorphisms and the Metabolic Syndrome in French-Canadian Youth

Marcil, Valérie, Amre, Devendra, Seidman, Ernest G., Boudreau, François, Gendron, Fernand P., Ménard, Daniel, Beaulieu, Jean François, Sinnett, Daniel, Lambert, Marie, Levy, Emile, Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

24

Evidence for Site-Specific Occupancy of the Mitochondrial Genome by Nuclear Transcription Factors

Marinov, Georgi K., Wang, Yun E., Chan, David, Wold, Barbara J., Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 10.21 MB

english, 2014

25

HNF4α — role in drug metabolism and potential drug target?

Wendy W Hwang-Verslues, Frances M Sladek

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

26

The Different Tissue Transcription Patterns of Genes for HNF-1, C/EBP, HNF-3, and HNF-4, Protein Factors that Govern Liver-Specific Transcription

Kleanthis G. Xanthopoulos, Vincent R. Prezioso, William S. Chen, Frances M. Sladek, Ricardo Cortese and James E. Darnell, Jr.

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 964 KB

english, 1991

27

Modulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1

Sladek, Frances M., Ruse, Michael D., Nepomuceno, Luviminda, Huang, Shih-Ming, Stallcup, Michael R.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.53 MB

english, 1999

28

Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats

Eugene Bolotin, Karthikeyani Chellappa, Wendy Hwang-Verslues, Jake M Schnabl, Chuhu Yang, Frances M Sladek

Journal:

Year:

2011

Language:

english

File:

PDF, 603 KB

english, 2011

29

Murine chromosomal location of four hepatocyte-enriched transcription factors: HNf-3α, HNF-3β, HNF-3γ, and HNF-4

Avraham, Karen B., Prezioso, Vincent R., Chen, William S., Lai, Eseng, Sladek, Frances M., Zhong, Weimin, Darnell, James E., Jenkins, Nancy A., Copeland, Neal G.

Journal:

Year:

1992

Language:

english

File:

PDF, 585 KB

english, 1992

30

Nuclear Receptor Hepatocyte Nuclear Factor 4α1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter

Hwang-Verslues, Wendy W., Sladek, Frances M.

Journal:

Molecular Endocrinology

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

31

Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes

Ahmed, Mohammed Seed, Pelletier, Julien, Leumann, Hannes, Gu, Harvest F., Östenson, Claes-Göran, Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 1.62 MB

english, 2015

32

HNF4α: a new biomarker in colon cancer?

Chellappa, Karthikeyani, Robertson, Graham R, Sladek, Frances M

Journal:

Biomarkers in Medicine

Year:

2012

Language:

english

File:

PDF, 749 KB

english, 2012

33

Identification of Putative Target Genes of the Transcription Factor RUNX2

Kuhlwilm, Martin, Davierwala, Armaity, Pääbo, Svante, Sladek, Frances M

Journal:

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

34

MENTAL ILLNESS AND POVERTY

Avraham, Karen B., Prezioso, Vincent R., Chen, William S., Lai, Eseng, Sladek, Frances M., Zhong, Weimin, Darnell, James E., Jenkins, Nancy A., Copeland, Neal G.

Journal:

Year:

1986

Language:

english

File:

PDF, 187 KB

english, 1986

35

Effect of dietary protein restriction on liver transcription factors

MARTEN, Norman W., SLADEK, Frances M., STRAUS, Daniel S.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 565 KB

english, 1996

36

Desperately Seeking…Something

Frances M Sladek

Journal:

Year:

2002

Language:

english

File:

PDF, 120 KB

english, 2002

37

Genome-Wide Binding Patterns of Thyroid Hormone Receptor Beta

Ayers, Stephen, Switnicki, Michal Piotr, Angajala, Anusha, Lammel, Jan, Arumanayagam, Anithachristy S., Webb, Paul, Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.96 MB

english, 2014

38

Role of Docosahexaenoic Acid Treatment in Improving Liver Histology in Pediatric Nonalcoholic Fatty Liver Disease

Nobili, Valerio, Carpino, Guido, Alisi, Anna, De Vito, Rita, Franchitto, Antonio, Alpini, Gianfranco, Onori, Paolo, Gaudio, Eugenio, Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 8.39 MB

english, 2014

39

Strategies for Individual Phenotyping of Linoleic and Arachidonic Acid Metabolism Using an Oral Glucose Tolerance Test

Saccenti, Edoardo, van Duynhoven, John, Jacobs, Doris M., Smilde, Age K., Hoefsloot, Huub C. J., Sladek, Frances M

Journal:

Year:

2015

Language:

english

File:

PDF, 780 KB

english, 2015

40

Expression of HNF-4α (MODY1), HNF-1β (MODY5), and HNF-1α (MODY3) proteins in the developing mouse pancreas

Takao Nammo, Kazuya Yamagata, Toshiya Tanaka, Tatsuhiko Kodama, Frances M. Sladek, Kenji Fukui, Fumie Katsube, Yoshifumi Sato, Jun-ichiro Miyagawa, Iichiro Shimomura

Journal:

Gene Expression Patterns

Year:

2008

Language:

english

File:

PDF, 7.79 MB

english, 2008

41

Identification of a Missing Link in the Evolution of an Enzyme into a Transcriptional Regulator

Durante-Rodríguez, Gonzalo, Mancheño, José Miguel, Rivas, Germán, Alfonso, Carlos, García, José Luis, Díaz, Eduardo, Carmona, Manuel, Sladek, Frances M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

42

Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters

Chuhu Yang, Eugene Bolotin, Tao Jiang, Frances M. Sladek, Ernest Martinez

Journal:

Year:

2007

Language:

english

File:

PDF, 1.17 MB

english, 2007

43

Down-Regulation of Hepatic HNF4α Gene Expression during Hyperinsulinemia via SREBPs

Xie, Xuefen, Liao, Hailing, Dang, Huaixin, Pang, Wei, Guan, Youfei, Wang, Xian, Shyy, John Y.-J., Zhu, Yi, Sladek, Frances M.

Journal:

Molecular Endocrinology

Year:

2009

Language:

english

File:

PDF, 462 KB

english, 2009

44

Characterization of the Mitochondrial Localization of the Nuclear Receptor SHP and Regulation of Its Subcellular Distribution by Interaction with Bcl2 and HNF4α

Zhang, Yuxia, Wang, Li, Sladek, Frances M.

Journal:

Year:

2013

Language:

english

File:

PDF, 9.08 MB

english, 2013

45

Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays

Eugene Bolotin, Hailing Liao, Tuong Chi Ta, Chuhu Yang, Wendy Hwang-Verslues, Jane R. Evans, Tao Jiang, Frances M. Sladek

Journal:

Year:

2010

Language:

english

File:

PDF, 2.19 MB

english, 2010

46

Latent trait cortisol (LTC) levels: Reliability, validity, and stability

Doane, Leah D., Chen, Frances R., Sladek, Michael R., Van Lenten, Scott A., Granger, Douglas A.

Journal:

Psychoneuroendocrinology

Year:

2015

Language:

english

File:

PDF, 874 KB

english, 2015

47

Mechanisms of liver-specific gene expression

Frances M. Sladek, James E. Darnell

Journal:

Current Biology

Year:

1992

Language:

english

File:

PDF, 107 KB

english, 1992

48

Mechanisms of liver-specific gene expression

Sladek, Frances M., Darnell, James E.

Journal:

Current Opinion in Genetics & Development

Year:

1992

Language:

english

File:

PDF, 437 KB

english, 1992

49

Functional and Molecular Characterization of Hyposensitive Underactive Bladder Tissue and Urine in Streptozotocin-Induced Diabetic Rat

Nirmal, Jayabalan, Tyagi, Pradeep, Chuang, Yao-Chi, Lee, Wei-Chia, Yoshimura, Naoki, Huang, Chao-Cheng, Rajaganapathy, Bharathi, Chancellor, Michael B., Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 604 KB

english, 2014

50

The Roles of Co-Chaperone CCRP/DNAJC7 in Cyp2b10 Gene Activation and Steatosis Development in Mouse Livers

Ohno, Marumi, Kanayama, Tomohiko, Moore, Rick, Ray, Manas, Negishi, Masahiko, Sladek, Frances M.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

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